The Fight of Our Lives: AIDS in America
David Levithan and Gabriel Duckels
Knopf Books for Young Readers
Published April 21, 2026

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About The Fight of Our Lives: AIDS in America

A thoughtful, poignant look at the AIDS crisis in the United States that includes primary source interviews, history, medical research, and cultural touchpoints.

The AIDS crisis in America is complex and composed of countless individual stories of grief, love, and advocacy. Its history shows the power of youth activism, how creativity and community can be vehicles for social change, and how bigotry and misinformation led to inequality in care.

The early days of the AIDS crisis saw LGBTQ+ and other marginalized communities making strides in the fight for equality. As many people in positions of power were slow to act or actively didn’t pay attention until their own communities were affected, the fight for equality turned into a fight for their lives. Grassroots efforts filled in gaps where mainstream medicine and politics failed, and over time, a cultural shift of awareness emerged, which led to more research and more treatments. And while the disease has transitioned from a death sentence to one that people can live full lives with, there are still people dying of HIV/AIDS today because they can’t access the care they need. The fight may have begun decades ago, but is not yet over.

Award-winning author David Levithan and University of Cambridge PhD Gabriel Duckels detail a brief history of the epidemic, touching on key moments and figures, such as Ryan White, ACT UP, Larry Kramer and Anthony Fauci, Pedro Zamora from MTV’s The Real World, and the Names Quilt. Threaded throughout are poems, essays, and other creative works, in addition to first-person interviews and narratives. The most important takeaway is that we must remember. We need to know what happened and why. Our voices are powerful, and they can make a difference.

My Review

This book is an intricate tapestry describing the nation’s history with AIDS as well as sharing deeply personal reflections and experiences and poetry, essays, and other creative works. The book describes the creation of the Names Quilt, which is made up of large fabric squares each representing the life of someone lost due to AIDS, and the book made me think of the quilt as well, because of how it’s pieced together and shares so many stories.

Some chapters outline the progression of research and treatment for AIDS during a short span of years. Juxtaposed with those are poems, interviews, and personal essays in which people share their own experience as a person who contracted HIV, the family member of someone with HIV, and/or an activist fighting for people with HIV/AIDS to have better access to treatment and to eliminate the stigma surrounding the diagnosis.

I think the authors did a great job trying to make sure that they presented information in context. For example, in the chapters talking about the work of Dr. Anthony Fauci, the authors highlight both the ways in which Fauci helped people gain better access to treatment and responded to harsh criticism from activists. But the authors also clearly point out the criticism of Dr. Fauci’s leadership and the cost of the decisions he made to those diagnosed with HIV/AIDS during that time.

The book explores the connection between the late/marginal response by the government to what amounted to an epidemic and the stigma that patients faced as a result of their diagnosis. The illustration of that connection feels particularly timely, as the culture and/or those in power embrace the stigmatization of certain groups today. It’s just as harmful now as it was then.

All in all, this is a powerful account of both history and humanity. It’s compelling and rich in its celebration of art, love, and life. What an incredible accomplishment. I won’t be at all surprised to see this book on awards lists later this year.

Content Notes

Recommended for Ages 16 up.

Profanity/Crude Language Content
Strong profanity used infrequently.

Romance/Sexual Content
References to sex. References to sexual assault. References to sex work. No sexual contact shown on page other than kissing.

Spiritual Content
References to personal faith. Reference to protests when the Catholic church said that using contraception was wrong. Reference to religious groups that cared for people with AIDS.

Violent Content
References to sexual assault. Descriptions of homophobia and transphobia. References to assault. Brief use of the f-slur.

Drug Content
References to drug abuse.

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